The Hidden Life of Spices – National Chemistry Week 2025

National Chemistry Week (#ACS_NCW) is celebrated this year during the week of October 19-25 with the theme “The Hidden Life of Spices.” Chemistry plays a crucial role in how spices can create various smells and flavors, while also acting as medicine or fabric dyes. Spices can be found typically as solids or in the form of oil, which is a hydrophobic liquid. Hydrophobic means that the substance does not like water. Chemists must use different methods while working in the laboratory to obtain these oils with methods including distillation, cold press, and more.

The structure of spices plays a huge role in how the spice is perceived by people. Even the smallest difference in structure can completely change how a spice tastes or smells. For example, did you know that celery and licorice have structures that have just one difference? These differences affect how receptors on our tongue and inside our nose interact with a spice, changing the way we perceive its smell and/or its taste.

There are a variety of chemicals in spices. In fact, spices are mixtures of various chemicals. Some chemicals found in spices include capsaicin, myristicin, and many more. Capsaicin is a chemical that makes peppers spicy. Myristicin is a chemical that gives nutmeg its flavor and aroma.”

Explore Educational Resources for younger children and General Interest Resources for college students and adults.

Celebrating Chemistry

Download English and Spanish versions of Celebrating Chemistry

How to Beat Spicy Pepper Heat

“Maybe you’ve heard that milk is the perfect way to extinguish that spicy food burn–but what if you can’t drink milk? This week our lactose-intolerant host, Sam, eats serrano peppers alongside lactose-tolerant George and they both try to find something that quenches the burn. Spoiler alert: One of them does a heck of a lot better than the other.”

Hot pepper cure video

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Watch more Reactions Science Videos on YouTube about spices:

AllspiceThe World’s Most Misunderstood Spice: Allspice
CilantroWhy Do Some People Hate Cilantro?
GarlicYou Can Taste Garlic with Your Feet!?
KimchiWhat Makes Kimchi So Delicious?
PepperThe Chemistry of Pepper: The Spice that Changed the World
Pumpkin spicePumpkin spice vs. maple: Battle of the fall flavors
SaltWhy Does Salt Change the Taste of Everything?
SrirachaThe Chemistry of Sriracha: Hot Sauce Science
VanillaAre We Running Out of Vanilla? — Speaking of Chemistry
WasabiThe Truth About Wasabi – Speaking of Chemistry

Infographics from Compound Interest:

Chemistry of a Chili

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Chemistry of Ginger and Bingerbread

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Major organic compounds in herbs and spices

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