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DTSTART;TZID=America/Los_Angeles:20260601T150000
DTEND;TZID=America/Los_Angeles:20260601T160000
DTSTAMP:20260623T182332
CREATED:20260508T145947Z
LAST-MODIFIED:20260508T145947Z
UID:22717-1780326000-1780329600@www.siliconvalleyacs.org
SUMMARY:Chemically and Financially Sustainable Methods for Chemical Synthesis
DESCRIPTION:Prof. Isaiah R. Speight\, College of William and Mary\nSponsored by Stanford Department of Chemistry\nJune 1\, 3:00-4:00 pm\, In-person\, Sapp Center Auditorium (STLC 111)\, Learn more\n\nSustainability has become a more prevalent topic in the chemical sciences due to increasing restrictions on solvents\, environmental impacts from chemistry\, and growing community concern about chemical impact. Our group is taking a broadened approach to sustainability by looking at three topic areas: Synthetic Sustainability\, Financial Sustainability\, and Educational Sustainability. The seminar will cover our group’s advances in solvent-free organic chemistry\, and 3D printed reaction vessels. \nAbout the Speaker\nDr. Isaiah Speight is an assistant professor at William & Mary in Williamsburg\, VA. He received his B.S. in Chemistry from Norfolk State University and his Ph.D. in chemistry from Vanderbilt University with Dr. Timothy Hanusa.  During his Ph.D.\, he developed mechanochemical methods towards a wide range of inorganic and organometallic complexes. Dr. Speight was also a visiting scientist at AbbVie where he developed a scalable and continuous method for the early steps of the synthesis of Upadacitnib (Rinvoq). Currently\, the Speight research group is tackling challenges in sustainable chemical synthesis. His group is a part of the NSF Center for Mechanical Control of Chemistry and has collaborative partnerships within the pharmaceutical industry. Dr. Speight is also the chapter advisor for W&M’s NOBCChE chapter and was previously a NOBCChE National Board Member.
URL:https://www.siliconvalleyacs.org/event/chemically-and-financially-sustainable-methods-for-chemical-synthesis/
LOCATION:In-person
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://www.siliconvalleyacs.org/wp-content/uploads/2026/05/Isiah-Speight-e1778252298531.jpg
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20260518T150000
DTEND;TZID=America/Los_Angeles:20260518T160000
DTSTAMP:20260623T182332
CREATED:20260508T143152Z
LAST-MODIFIED:20260508T143239Z
UID:22705-1779116400-1779120000@www.siliconvalleyacs.org
SUMMARY:Light-Driven Fuel Production at Passivated Silicon Photoelectrodes
DESCRIPTION:Prof. Jillian Dempsey\, University of North Carolina\, Chapel Hill\nSponsored by Stanford Department of Chemistry\nMay 18\, 3:00-4:00 pm\, In-person\, Sapp Center Auditorium (STLC 111)\, Learn more\n\nCoatings and termination strategies for silicon photoelectrodes are crucial to protect the semiconductor from detrimental and uncontrolled oxidation during photoelectrochemical reactions that produce chemicals and fuels. However\, these modifications must not inhibit interfacial charge transfer to catalysts and mediators. Terminating the silicon lattice with organic moieties affords stable photoelectrodes that exhibit large photovoltages. Methyl-terminated silicon can be employed to drive the selective reduction of CO2 by molecular catalysts without the competitive hydrogen evolution observed for H-terminated electrodes. Direct attachment of the catalyst is also possible\, but the passivation is below unity\, and defects at the surface lower photovoltage and selectivity. Collectively\, these studies provide key foundations for hybrid photoelectrodes that drive fuel production with sunlight. \nAbout the Speaker\nJillian L. Dempsey is a professor at the University of North Carolina at Chapel Hill. She is currently the Director of the Center for Hybrid Approaches in Solar Energy to Liquid Fuels (CHASE) and an Associate Editor for ACS Electrochemistry. \nJillian received her S.B. from the Massachusetts Institute of Technology in 2005 where she worked in the laboratory of Prof. Daniel G. Nocera. As an NSF Graduate Research Fellow\, she carried out research with Prof. Harry B. Gray and Dr. Jay R. Winkler at the California Institute of Technology\, receiving her PhD in 2011. From 2011–2012 she was an NSF ACC Postdoctoral Fellow with Daniel R. Gamelin at the University of Washington. \nIn 2012\, Jillian joined the faculty at the University of North Carolina at Chapel Hill. Her research group explores charge transfer processes associated with energy capture and conversion\, including proton-coupled electron transfer reactions and electron transfer across interfaces. Her research bridges molecular and materials chemistry and relies heavily on methods of physical inorganic chemistry\, including transient absorption spectroscopy and electrochemistry. \nShe has received numerous awards including the Harry B. Gray Award for Creative Work in Inorganic Chemistry by a Young Investigator (2019)\, the J. Carlyle Sitterson Award for Teaching First-Year Students (2017)\, a Sloan Research Fellowship (2016)\, a Packard Fellowship for Science and Engineering (2015)\, the Agnes Fay Morgan Research Award (2020)\, and the University Award for Advancement of Women (2021).
URL:https://www.siliconvalleyacs.org/event/light-driven-fuel-production-at-passivated-silicon-photoelectrodes/
LOCATION:In-person
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://www.siliconvalleyacs.org/wp-content/uploads/2026/05/Jillian-Dempsey-e1778250746462.jpg
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250203T150000
DTEND;TZID=America/Los_Angeles:20250203T160000
DTSTAMP:20260623T182332
CREATED:20250112T231045Z
LAST-MODIFIED:20250112T231045Z
UID:21573-1738594800-1738598400@www.siliconvalleyacs.org
SUMMARY:Stanford Materials Chemistry Seminar\, Student-Hosted Colloquium
DESCRIPTION:Prof. Samuel Stupp\, Northwestern University\nSponsored by Stanford Chemistry Department\n3:00-4:00 pm\, Sapp Center Auditorium 111\, 376 Lomita Dr.\, Stanford Univ.\, Learn more\n\nAbout the Speaker\n“Samuel Stupp is Board of Trustees Professor of Materials Science and Engineering\, Chemistry\, Medicine\, and Biomedical Engineering at Northwestern University. He also directs Northwestern’s Center for Regenerative Nanomedicine. Stupp’s interdisciplinary research is focused on developing self-assembling supramolecular nanostructures and materials for functions relevant to renewable energy\, regenerative medicine\, and robotic soft matter. He is a member of the U.S. National Academy of Sciences\, the U.S. National Academy of Engineering\, the American Academy of Arts and Sciences\, the Royal Spanish Academy\, the National Academy of Sciences of Latin America\, the National Academy of Sciences of Costa Rica\, and the U.S. National Academy of Inventors. \nStupp has won numerous awards over the course of his career\, including three American Chemical Society national awards: the Award in Polymer Chemistry\, the Ronald Breslow Award for Achievement in Biomimetic Chemistry\, and the Ralph F. Hirschmann Award in Peptide Chemistry. He recently received the 2022 Materials Research Society Von Hippel Award\, the highest honor awarded by this society. Other awards include the Department of Energy Prize for Outstanding Scientific Accomplishment in Materials Chemistry\, the Materials Research Society Medal Award\, the Royal Society of Chemistry Award in Soft Matter and Biophysical Chemistry\, and the Nanoscience Prize from the International Society for Nanoscale Science\, Computation\, and Engineering\, which recognizes lifelong achievement in the field.”
URL:https://www.siliconvalleyacs.org/event/stanford-materials-chemistry-seminar-student-hosted-colloquium/
LOCATION:In-person
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/png:https://www.siliconvalleyacs.org/wp-content/uploads/2025/01/Samuel-Stupp.png
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250113T150000
DTEND;TZID=America/Los_Angeles:20250113T160000
DTSTAMP:20260623T182332
CREATED:20250112T183000Z
LAST-MODIFIED:20250112T192228Z
UID:21533-1736780400-1736784000@www.siliconvalleyacs.org
SUMMARY:Strategies to Discover\, Design\, and Synthesize Unnatural Bioactive Peptides
DESCRIPTION:Dr. Carly Schissel\, University of California\, Berkeley\nSponsored by Stanford Chemistry Department\n3:00-4:00 pm\, Sapp Center Auditorium 111\, 376 Lomita Dr.\, Stanford Univ.\, Learn more\n\n“Peptide therapeutics are a rapidly expanding frontier in drug development. New methods that address challenges in the discovery\, design\, and synthesis of bioactive peptides are needed to advance these molecules as medicines. One of the most important roadblocks that macromolecular drugs face is their inability to reach intracellular targets. I will demonstrate new approaches for the design and synthesis of unnatural bioactive peptides. First\, we used machine learning for the de novo design of nuclear-targeting miniproteins to traffic macromolecular cargo to the nucleus of cells. We found that the model was able to predict new sequences with activities extrapolated beyond the training dataset\, resulting in the most active variants yet. Next\, we demonstrated a method for in-cell penetration selection–mass spectrometry to discover cytosol-targeting peptides from a synthetic library. Novel unnatural sequences found from the cytosol trafficked oligonucleotide cargo to the nucleus better than those found in whole cell extracts. A key outcome of these efforts was that the presence of unnatural amino acids with extended backbones conferred enhanced bioactivity. The ribosomal synthesis of proteins and peptides with unnatural peptide backbones is thus of critical importance. In the second part of the presentation\, we developed post-translational acyl shift reactions to install internal diketones\, heterocycles\, and extended backbones in ribosomal peptides and proteins. These works advance the therapeutic potential of peptides by both developing new bioactive sequences and enabling their biological synthesis. \nAbout the Speaker\nCarly grew up in San Diego\, California\, and earned her BA in Chemistry from Williams College\, where she worked under the mentorship of Prof. Thomas Smith to complete the total synthesis of the polyketide Jerangolid D. She pursued her Ph.D. in Chemistry at the Massachusetts Institute of Technology\, working with Prof. Brad Pentelute. Her doctoral research focused on designing peptide sequences for the nuclear delivery of macromolecules\, employing machine learning-guided design and in-cell selection strategies. In March 2022\, Carly joined the University of California\, Berkeley\, as a Miller Institute Postdoctoral Fellow\, hosted by Prof. Alanna Schepartz. Her current research centers on developing peptide backbone editing reactions\, including the substitution of canonical amide bonds with carbon-carbon bonds.” \nHost: Steven Banik
URL:https://www.siliconvalleyacs.org/event/strategies-to-discover-design-and-synthesize-unnatural-bioactive-peptides/
LOCATION:In-person
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://www.siliconvalleyacs.org/wp-content/uploads/2025/01/carly_schissel_0.jpg
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